Application Note

Using Microfluidic Modulation Spectroscopy to Determine the Structural Effect of pH on the Peptide Hormone Insulin 

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Application note

This Application Note Includes:

  • Determines the structural effects of low pH on insulin using MMS
  • Measures protein secondary structure by combining infrared spectroscopy
    with microfluidics to enhance sensitivity and accuracy
  • Achieves higher sensitivity across a wider concentration range compared
    to current FTIR techniques

Protein Analysis Tools: Characterizing Secondary Structure Analysis Of Insulin

Secondary structure characterization is an essential part of drug development, however, the tools for measuring secondary structure of small proteins and peptides are limited. Microfluidic Modulation Spectroscopy (MMS), a new characterization platform that powers the AQS3pro system developed by RedshiftBio, measures protein secondary structure by combining infrared spectroscopy with microfluidics to enhance sensitivity and accuracy.

Change How You See Biomolecules

Microfluidic Modulation Spectroscopy provides a powerful alternative, producing consistently reproducible data that goes beyond that supplied by current techniques. The high-performance fully automated AQS3pro system and AQS3delta analytics package allow scientists to quickly and easily run samples, process data and gain insight.


Next generation in protein structure determination.

The AQS³pro powered by Microfluidic Modulation Spectroscopy is the next generation infrared based spectroscopy platform for protein structure determination. It represents a novel tool that will strengthen you bioanalytical tool kit and provide critical insights into protein based drug development.
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